Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759488 | 0.77 | MAPT (0.50) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL15082112 | 0.76 | ALDH1A1 (0.47) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL3868313 | 0.75 | ALDH1A1 (0.56) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL7515416 | 0.75 | ALDH1A1 (0.57) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL3296417 | 0.74 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL1032814 | 0.72 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL6161726 | 0.72 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL30128616 | 0.72 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL3990991 | 0.71 | TXNRD1 (0.75) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL6039967 | 0.71 | TXNRD1 (0.74) | TXNRD1TXNRD3TXNRD2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060113-A1 | SULFENAMIDE COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060113-A1 | SULFENAMIDE COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-05-19 | — | — | WO | disclosed |