SCHEMBL17595407

SCHEMBL17595407

C[Si](C)(C)OP(=O)(CCCCCCCCCCCCN)O[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 3/20 0.38
GABBR1 Q9UBS5 3/20 0.38
GABRR1 P24046 1/20 0.36
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.35
THPO P40225 1/20 0.35
LMNA P02545 3/20 0.34
BLM P54132 3/20 0.34
DNM1 Q05193 4/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CA5B Q9Y2D0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25230931 0.82 ALDH1A1 (0.36) GABBR2GABBR1GABRR1TSHRCYP1A2
SCHEMBL12815010 0.81 LPAR3 (0.46)
SCHEMBL2218116 0.81 LPAR3 (0.46)
SCHEMBL17865474 0.76 GABBR2 (0.40) GABBR2GABBR1GABRR1CYP3A4
SCHEMBL16385092 0.76 TSHR (0.39) GABBR2GABBR1TSHRCYP1A2THPO
SCHEMBL14124631 0.74
SCHEMBL13948782 0.73
SCHEMBL28670831 0.73 GABBR2 (0.41) GABBR2GABBR1GABRR1TSHRCYP1A2
SCHEMBL5841645 0.72 PPARD (0.50) GABBR2GABBR1TSHRCYP1A2DNM1
SCHEMBL15927961 0.72 PPARD (0.50) GABBR2GABBR1TSHRCYP1A2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11945898-B2 Functional polymer SUSOS AG (CH) 2024-04-02 US disclosed
US-20210087309-A1 FUNCTIONAL POLYMER SUSOS AG (CH) 2021-03-25 US disclosed
US-10882931-B2 Functional polymer SUSOS AG (CH) 2021-01-05 US disclosed
EP-3191559-B1 FUNCTIONAL POLYMER SUSOS AG (CH) 2018-10-31 EP disclosed
US-20170291971-A1 FUNCTIONAL POLYMER SUSOS AG (CH) 2017-10-12 US disclosed
EP-3191559-A1 FUNCTIONAL POLYMER SuSoS AG (CH) 2017-07-19 EP disclosed
WO-2016037630-A1 FUNCTIONAL POLYMER SUSOS AG (CH) 2016-03-17 WO disclosed