Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12815010 | 1.00 | LPAR3 (0.46) | LPAR3LPAR2FAAHTRPM8LPAR1 | |
| SCHEMBL17865474 | 0.91 | GABBR2 (0.40) | LPAR3LPAR2FAAHTRPM8 | |
| SCHEMBL15430102 | 0.90 | FAAH (0.50) | LPAR3LPAR2FAAHTRPM8 | |
| SCHEMBL18109773 | 0.82 | LPAR3 (0.42) | LPAR3LPAR2FAAHTRPM8LPAR1 | |
| SCHEMBL17865471 | 0.81 | L3MBTL1 (0.33) | — | |
| SCHEMBL17595407 | 0.81 | GABBR2 (0.38) | — | |
| SCHEMBL1455833 | 0.79 | LPAR3 (0.54) | LPAR3LPAR2FAAHTRPM8LPAR1 | |
| SCHEMBL14124631 | 0.76 | — | — | |
| SCHEMBL28075416 | 0.75 | LPAR3 (0.64) | LPAR3LPAR2 | |
| SCHEMBL5035905 | 0.75 | FAAH (0.61) | LPAR3LPAR2FAAHTRPM8LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435635-B2 | Chemical modification of nanocrystal surfaces | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110177340-A1 | Chemical Modification of Nanocrystal Surfaces | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |