Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596173 | 0.75 | CYP2C9 (0.44) | NR1H2NR1H3CYP2C9CYP2C19DHODH | |
| SCHEMBL17596454 | 0.73 | NR1H2 (0.46) | NR1H2NR1H3CYP2C9CYP2C19DHODH | |
| SCHEMBL1124262 | 0.73 | NR1H2 (0.79) | NR1H2NR1H3FABP4 | |
| SCHEMBL1124099 | 0.72 | NR1H2 (0.73) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL1125459 | 0.68 | NR1H2 (0.83) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL27673920 | 0.68 | NR1H2 (0.88) | NR1H2NR1H3 | |
| SCHEMBL1125727 | 0.67 | NR1H2 (0.87) | NR1H2NR1H3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL24525171 | 0.67 | ASPH (0.39) | CYP2C9DHODHASPHKMT2AGABRA5 | |
| SCHEMBL24525494 | 0.67 | ASPH (0.39) | DHODHASPHGABRA5 | |
| SCHEMBL6703940 | 0.66 | FABP4 (0.70) | NR1H2NR1H3DHODHFABP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191465-B1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-19 | — | — | EP | disclosed |
| US-9980486-B2 | Herbicidal quinolines | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20170251670-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-07 | — | — | US | disclosed |
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170251670-A1 | HERBICIDAL QUINOLINES | NQO2, DDT, ATP1B1 | NR1H2 2118/4885NR1H3 2267/4885CYP2C9 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.