Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719643 | 0.98 | TLR8 (0.50) | TLR8NQO2LIPGKCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28910209 | 0.97 | TLR8 (0.49) | TLR8NQO2LIPGKCNH2ALDH1A1 | |
| SCHEMBL28672379 | 0.89 | ALDH1A1 (0.48) | TLR8NQO2KCNH2ALDH1A1GAA | |
| SCHEMBL17289226 | 0.82 | NQO2 (0.44) | TLR8NQO2ALDH1A1GAAMAPT | |
| SCHEMBL3414003 | 0.81 | NQO2 (0.50) | NQO2ALDH1A1GAAMAPTRAB9A | |
| Phosphine SCHEMBL28356756 | 0.80 | TLR8 (0.61) | TLR8LIPGKCNH2ALDH1A1MAPT | |
| SCHEMBL6818826 | 0.80 | TLR8 (0.47) | TLR8LIPGKCNH2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6769346 | 0.79 | NQO2 (0.48) | NQO2ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7600918 | 0.77 | TLR8 (0.61) | TLR8ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL29287282 | 0.76 | LIPG (0.67) | LIPGKCNH2MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115403522-A | Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | claimed |
| EP-3900742-B1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | SEAGEN INC (US) | 2024-05-15 | — | — | EP | disclosed |
| CN-114732916-B | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-115403523-A | Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-115403522-A | Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-114732916-A | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-107108694-B | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-114133395-A | Pyrroloquinazolinone skeleton compound with fluorescence characteristic, preparation method and application | 中国科学院成都有机化学有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113827737-A | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2021-12-24 | — | — | CN | disclosed |
| EP-3900742-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | Seagen Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3191502-B1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | SEAGEN INC (US) | 2021-04-21 | — | — | EP | disclosed |
| CN-109305937-A | Quinoline derivatives and preparation method thereof and the application in neuroprotection | 王萍 | 2019-02-05 | — | — | CN | disclosed |
| CN-108947969-A | Quinoline derivatives and preparation method thereof with neuroprotection | 王萍 | 2018-12-07 | — | — | CN | disclosed |
| CN-108929318-A | 2- furans aldehyde compound and its application in Alzheimer disease drugs | 王萍 | 2018-12-04 | — | — | CN | disclosed |
| US-20170247412-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | SEATTLE GENETICS, INC. (US) | 2017-08-31 | — | — | US | disclosed |
| EP-3191502-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | Seattle Genetics, Inc. (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016040684-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | SEATTLE GENETICS, INC (US) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247412-A1 | TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES | CD47, CD44, MSR1 | TLR8 317/4885NQO2 651/4885LIPG 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.