Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 4/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919146 | 0.87 | HINT1 (0.58) | HINT1NT5EFUT5PNP | |
| SCHEMBL3278964 | 0.85 | KDM4E (0.48) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL17597173 | 0.81 | POLB (0.56) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL8057804 | 0.80 | POLB (0.65) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL3751858 | 0.80 | POLB (0.67) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL3744960 | 0.79 | POLB (0.68) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL338650 | 0.79 | POLB (0.70) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL16359949 | 0.79 | POLB (0.70) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL30591564 | 0.79 | HINT1 (0.49) | HINT1NT5EFUT5PNP | |
| SCHEMBL367384 | 0.79 | POLB (0.65) | POLBP2RY2P2RY4P2RY6HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191605-A1 | A DROPLET-BASED METHOD AND APPARATUS FOR COMPOSITE SINGLE-CELL NUCLEIC ACID ANALYSIS | The Broad Institute, Inc. (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016040476-A1 | A DROPLET-BASED METHOD AND APPARATUS FOR COMPOSITE SINGLE-CELL NUCLEIC ACID ANALYSIS | THE BROAD INSTITUTE, INC. (US) | 2016-03-17 | — | — | WO | disclosed |