Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | HTR6 | P50406 | 12/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17597311 | 0.93 | MEN1 (0.85) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL10345778 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL29559974 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL430473 | 0.82 | HTR6 (1.00) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL17423758 | 0.81 | MEN1 (0.62) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL7245919 | 0.81 | HTR6 (0.69) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL1892670 | 0.81 | HTR6 (0.78) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL27879729 | 0.78 | MEN1 (0.72) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL3965144 | 0.76 | HTR6 (0.70) | MEN1KMT2AHTR6POLBL3MBTL1 | |
| SCHEMBL28857217 | 0.76 | MEN1 (0.70) | MEN1KMT2AHTR6POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040764-A1 | CARBONYL LINKED BICYCLIC HETEROARYL N-BENZIMIDAZOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS | SPERO THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |