Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | KDM4A | O75164 | 2/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007824 | 0.98 | SIGMAR1 (0.70) | SIGMAR1MAPTRXFP1HDAC3MAPK1 | |
| Hydrochloric Acid SCHEMBL9554752 | 0.93 | SIGMAR1 (0.62) | SIGMAR1MAPTRXFP1HDAC3MAPK1 | |
| Hydrochloric Acid SCHEMBL9553898 | 0.86 | LTA4H (0.57) | SIGMAR1MAPTRXFP1HDAC3MAPK1 | |
| SCHEMBL7398852 | 0.85 | KDM4A (0.74) | SIGMAR1KDM4AKDM4CTMEM97 | |
| SCHEMBL8802332 | 0.84 | SIGMAR1 (0.59) | SIGMAR1HDAC1KDM4AKDM4CTHRA | |
| SCHEMBL13783920 | 0.84 | CYP1A2 (0.67) | SIGMAR1HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL9397361 | 0.84 | SIGMAR1 (0.70) | SIGMAR1MAPTRXFP1HDAC3MAPK1 | |
| Hydrochloric Acid SCHEMBL9397399 | 0.84 | SIGMAR1 (0.70) | SIGMAR1MAPTRXFP1HDAC3MAPK1 | |
| SCHEMBL8550243 | 0.83 | SIGMAR1 (0.62) | SIGMAR1SLC6A3THRATHRBALOX5 | |
| SCHEMBL7205122 | 0.83 | KDM4A (0.76) | SIGMAR1MAPTRXFP1KDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995612-A1 | Novel non-natural amino acids, their process of preparation and uses thereof | Université de Strasbourg (FR) | 2016-03-16 | — | — | EP | disclosed |