Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9554752 | 0.87 | SIGMAR1 (0.62) | SIGMAR1THRATHRBTMEM97FDPS | |
| SCHEMBL27917087 | 0.87 | SIGMAR1 (0.62) | SIGMAR1THRATHRBTMEM97FDPS | |
| SCHEMBL21568869 | 0.87 | SIGMAR1 (0.64) | SIGMAR1ALDH1A1THRATHRBFDPS | |
| Demelverine SCHEMBL7778459 | 0.86 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1THRATHRBTMEM97 | |
| SCHEMBL8547157 | 0.85 | SIGMAR1 (0.58) | SIGMAR1ALDH1A1TMEM97 | |
| SCHEMBL17598201 | 0.83 | SIGMAR1 (0.67) | SIGMAR1THRATHRBTMEM97SLC6A3 | |
| SCHEMBL22450018 | 0.83 | HDAC1 (0.66) | SIGMAR1ALOX5 | |
| SCHEMBL1007824 | 0.82 | SIGMAR1 (0.70) | SIGMAR1THRATHRBSLC6A3ALOX5 | |
| SCHEMBL9554296 | 0.81 | ALOX5 (0.69) | SIGMAR1THRATHRBALOX5 | |
| SCHEMBL110777 | 0.80 | ALDH1A1 (0.76) | ALDH1A1SLC6A3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824917-A2 | Use of a serotonin 5-HTlf agonist in the manufacture of a medicament for treating or ameliorating the symptoms of common cold or allergic rhinitis | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |