Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.48 |
| ▸ | ACLY | P53396 | 5/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599483 | 0.89 | MEN1 (0.56) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599423 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599467 | 0.85 | KMT2A (0.55) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599510 | 0.83 | KMT2A (0.53) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599470 | 0.81 | MEN1 (0.46) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599463 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599466 | 0.80 | KMT2A (0.51) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599429 | 0.80 | KMT2A (0.51) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599431 | 0.79 | KMT2A (0.50) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL17599460 | 0.78 | HPGD (0.51) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998295-A1 | Aryl substituted naphthyl sulfonamide derivatives as keap-1 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | claimed |
| EP-2998295-A1 | Aryl substituted naphthyl sulfonamide derivatives as keap-1 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |