SCHEMBL1760137

SCHEMBL1760137

CCOP(=O)(Cc1ccc(I)cc1)OCC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.42
TSHR P16473 2/20 0.41
HDAC1 Q13547 1/20 0.39
CCNT1 O60563 2/20 0.38
CDK9 P50750 2/20 0.38
TLR8 Q9NR97 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 2/20 0.36
CYP3A4 P08684 2/20 0.36
IDO1 P14902 2/20 0.36
PPARD Q03181 1/20 0.36
HTT P42858 1/20 0.36
MAPK1 P28482 1/20 0.36
APP P05067 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
EGFR P00533 1/20 0.35
PTK2 Q05397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375825 0.90 TSHR (0.50) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL16062693 0.84 POLB (0.46) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL2493713 0.84 TSHR (0.44) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL12648165 0.83 PPARD (0.42) HDAC1POLBCYP3A4IDO1PPARD
SCHEMBL9502383 0.83 HDAC1 (0.50) HDAC1POLBMAPT
SCHEMBL23822678 0.82 TSHR (0.43) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL915242 0.82 TSHR (0.43) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL25923558 0.82 TSHR (0.43) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL13981237 0.81 ENPP2 (0.51) NPY5RTSHRHDAC1CCNT1CDK9
SCHEMBL675546 0.81 KMT2A (0.42) NPY5RTSHRHDAC1CCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024199444-A1 HETEROAROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海翊维康医药有限责任公司 2024-10-03 WO disclosed
US-20230201382-A1 RADIOLIGANDS FOR MYELIN NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-06-29 US disclosed
WO-2023061999-A1 PROCESS FOR PREPARING A PHENOLIC HYDROCARBON STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2023-04-20 WO disclosed
EP-4166531-A1 PROCESS FOR PREPARING A PHENOLIC HYDROCARBON Studiengesellschaft Kohle mbH (DE) 2023-04-19 EP disclosed
US-20210128756-A1 RADIOLIGANDS FOR MYELIN NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-05-06 US disclosed
US-10765763-B2 Radioligands for myelin CASE WESTERN RESERVE UNIVERSITY (US) 2020-09-08 US disclosed
US-20190134232-A1 RADIOLIGANDS FOR MYELIN CASE WESTERN RESERVE UNIVERSITY 2019-05-09 US disclosed
US-9541848-B2 Electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2017-01-10 US disclosed
US-9541848-B2 Electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2017-01-10 US disclosed
US-9541848-B2 Electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2017-01-10 US disclosed
US-7201976-B2 Organic electroluminescence material and electroluminescence device using the same SAMSUNG SDI CO., LTD. (KR) 2007-04-10 US disclosed
US-7201976-B2 Organic electroluminescence material and electroluminescence device using the same SAMSUNG SDI CO., LTD. (KR) 2007-04-10 US disclosed
EP-1432453-A4 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES UNIV PENNSYLVANIA (US) 2007-01-24 EP disclosed
US-20060263639-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2006-11-23 US disclosed
US-20060002853-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-01-05 US disclosed
EP-1432453-A1 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES The Trustees of The University of Pennsylvania (US) 2004-06-30 EP disclosed
US-20040018387-A1 Organic electroluminescence material and electroluminescence device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2004-01-29 US disclosed
US-20030149250-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2003-08-07 US disclosed
WO-2003018070-A1 STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2003-03-06 WO disclosed
EP-1074601-A2 Organic electroluminescent material and electroluminescent device using the same NEC CORPORATION (JP) 2001-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190134232-A1 RADIOLIGANDS FOR MYELIN MAG, PMP22, MYT1 NPY5R 2502/4885TSHR 275/4885HDAC1 3006/4885
US-20230201382-A1 RADIOLIGANDS FOR MYELIN MAG, PMP22, MYT1 NPY5R 998/4885TSHR 721/4885HDAC1 2694/4885
US-20060002853-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques APP, APBA1, PSEN1 NPY5R 2277/4885TSHR 4641/4885HDAC1 4353/4885
US-20060263639-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELECTROLUMINESCENCE DEVICE USING THE SAME ELAVL1, L1CAM, ELOB NPY5R 3520/4885TSHR 3669/4885HDAC1 2211/4885
US-20210128756-A1 RADIOLIGANDS FOR MYELIN MAG, PMP22, MYT1 NPY5R 2502/4885TSHR 275/4885HDAC1 3006/4885
US-10765763-B2 Radioligands for myelin MAG, PMP22, MYT1 NPY5R 2502/4885TSHR 275/4885HDAC1 3006/4885
US-20040018387-A1 Organic electroluminescence material and electroluminescence device using the same LEF1, ELAVL1, ELP1 NPY5R 3622/4885TSHR 4055/4885HDAC1 1230/4885
US-20030149250-A1 Stilbene derivatives and their use for binding and imaging amyloid plaques APP, APBA1, PSEN1 NPY5R 2277/4885TSHR 4641/4885HDAC1 4353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.