Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167951 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL9335465 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL5176869 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL21256944 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL12744307 | 0.81 | ALDH1A1 (0.78) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL9339153 | 0.80 | MEN1 (0.45) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL10889115 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL5743526 | 0.79 | KCNH3 (0.56) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL7650055 | 0.79 | KCNH3 (0.56) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL735232 | 0.79 | MMP8 (0.50) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083391-A1 | TRICYCLIC PIPERAZINE DERIVATIVE | SUNOVION PHARMACEUTICALS INC (US) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083391-A1 | TRICYCLIC PIPERAZINE DERIVATIVE | PDE3A, PDE5A, PDE2A | ALDH1A1 247/4885TDP1 48/4885TSHR 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.