Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.33 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.32 |
| ▸ | CLK3 | P49761 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103133 | 0.78 | KDM4C (0.56) | KDM4CKDM5AKDM5B | |
| SCHEMBL17604583 | 0.77 | PHF8 (0.68) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL4822648 | 0.76 | MAOA (0.41) | MAOAMAOBNISCHBRS3 | |
| SCHEMBL17604547 | 0.69 | PHF8 (0.66) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL12011588 | 0.66 | NPC1 (0.44) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16095231 | 0.66 | KDM4C (0.58) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL12011581 | 0.66 | CYP11B2 (0.49) | — | |
| SCHEMBL12011584 | 0.65 | SMN1; SMN2 (0.44) | ROCK2 | |
| SCHEMBL19358820 | 0.65 | KDM5A (0.36) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL17604606 | 0.65 | KDM5A (0.61) | PHF8KDM2BCYP2C9CYP2C19KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |