Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12011588 | 0.85 | NPC1 (0.44) | ALDH1A1 | |
| SCHEMBL27584275 | 0.81 | ALDH1A1 (0.43) | CYP2D6ALDH1A1 | |
| SCHEMBL1927628 | 0.81 | ROCK2 (0.44) | MAOATAAR1ADORA2AADORA1SLC6A2 | |
| SCHEMBL1927631 | 0.81 | ROCK2 (0.44) | MAOATAAR1ADORA2AADORA1SLC6A2 | |
| SCHEMBL1927633 | 0.81 | ROCK2 (0.44) | MAOATAAR1ADORA2AADORA1SLC6A2 | |
| SCHEMBL12011584 | 0.81 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL1696579 | 0.80 | ADORA1 (0.47) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL12011581 | 0.79 | CYP11B2 (0.49) | — | |
| Benzylamine SCHEMBL27584277 | 0.79 | LOXL2 (0.41) | MAOATAAR1ADORA2AADORA1SLC6A2 | |
| SCHEMBL1927511 | 0.78 | POLB (0.43) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402602-B2 | Imidazole derivatives modulating the sodium channels | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) | 2008-07-22 | — | — | US | disclosed |
| US-20060069146-A1 | Imidazole derivatives modulating the sodium channels | SCRAS | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069146-A1 | Imidazole derivatives modulating the sodium channels | SCN1B, SCN1A, SCN2B | MAOA 510/4885MAOB 450/4885NISCH 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.