Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604604 | 0.88 | MPO (0.39) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL17604679 | 0.78 | MPO (0.43) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL17604681 | 0.65 | MAPT (0.39) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL2678949 | 0.64 | MPO (0.80) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL343630 | 0.64 | MPO (0.80) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL808434 | 0.64 | MPO (0.58) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL28188923 | 0.62 | MPO (0.76) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL1904111 | 0.62 | ALDH1A1 (0.70) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL9648378 | 0.62 | MPO (0.56) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL2834465 | 0.62 | ADORA3 (0.61) | MPOCYP3A4BLMKDM5AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194359-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | Intrexon Corporation (US) | 2017-07-26 | — | — | EP | claimed |
| WO-2016044390-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORPORATION (US) | 2016-03-24 | — | — | WO | claimed |