Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604630 | 0.88 | MPO (0.41) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL17604678 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL17620525 | 0.71 | ALDH1A1 (0.57) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL20481887 | 0.69 | TSHR (0.42) | ALDH1A1KDM4E | |
| SCHEMBL6582556 | 0.68 | NPC1 (0.62) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL19608153 | 0.67 | CA12 (0.46) | BLMALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL17604604 | 0.67 | MPO (0.39) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL17604681 | 0.67 | MAPT (0.39) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL17604649 | 0.67 | MPO (0.39) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL1395940 | 0.67 | TAS1R3 (0.63) | KDM4ESMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194359-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | Intrexon Corporation (US) | 2017-07-26 | — | — | EP | claimed |
| WO-2016044390-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORPORATION (US) | 2016-03-24 | — | — | WO | claimed |