Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511851 | 1.00 | L3MBTL1 (0.54) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL30640439 | 0.88 | L3MBTL1 (0.50) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL10819614 | 0.88 | L3MBTL1 (0.50) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL2167353 | 0.88 | L3MBTL1 (0.50) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL31370630 | 0.88 | L3MBTL1 (0.50) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL25361693 | 0.88 | L3MBTL1 (0.50) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL10820370 | 0.86 | L3MBTL1 (0.52) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL31370731 | 0.85 | L3MBTL1 (0.48) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL1520892 | 0.83 | L3MBTL1 (0.70) | L3MBTL1EPHX1HTR6CHRM2CHRM4 | |
| SCHEMBL13230289 | 0.82 | L3MBTL1 (0.46) | L3MBTL1EPHX1HTR6CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067950-B1 | NEO-TRYPTOPHAN | MAYO FOUNDATION (US) | 2008-05-14 | — | — | EP | claimed |
| US-20030166505-A1 | Neo-tryptophan | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, A MINNESOTA CORPORATION | 2003-09-04 | — | — | US | claimed |
| US-20010027174-A1 | Neo-tryptophan | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH MINNESOTA CORPORATION | 2001-10-04 | — | — | US | claimed |
| EP-1067950-A4 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL (US) | 2001-09-05 | — | — | EP | claimed |
| US-6214790-B1 | POLYPEPTIDES OF NEOTRYPTOPHAN AND SYNTHESIS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2001-04-10 | — | — | US | claimed |
| EP-1067950-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999052539-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-10-21 | — | — | WO | claimed |
| CN-118255777-A | Synthesis and application of CDK7 inhibitors | 晶锐医药(苏州)有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023158725-A1 | ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | LUCY THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| US-9505753-B2 | Inhibitors of D-amino acid oxidase | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150218156-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-08-06 | — | — | US | disclosed |
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |
| US-20130210740-A1 | NEO-TRYPTOPHAN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-08-15 | — | — | US | disclosed |
| WO-2004049901-A2 | METHODS OF TREATING CEREBRAL ISCHEMIA | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20030166505-A1 | Neo-tryptophan | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, A MINNESOTA CORPORATION | 2003-09-04 | — | — | US | disclosed |
| US-20010027174-A1 | Neo-tryptophan | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH MINNESOTA CORPORATION | 2001-10-04 | — | — | US | disclosed |
| EP-1067950-A4 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6214790-B1 | POLYPEPTIDES OF NEOTRYPTOPHAN AND SYNTHESIS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2001-04-10 | — | — | US | disclosed |
| EP-1067950-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999052539-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218156-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, GRIN2A | L3MBTL1 1521/4885EPHX1 600/4885HTR6 481/4885 |
| US-20030166505-A1 | Neo-tryptophan | NTSR1, NTSR2, TPH1 | L3MBTL1 1214/4885EPHX1 3078/4885HTR6 12/4885 |
| US-20010027174-A1 | Neo-tryptophan | NTSR1, NTSR2, TPH1 | L3MBTL1 1214/4885EPHX1 3078/4885HTR6 12/4885 |
| US-20130210740-A1 | NEO-TRYPTOPHAN | OPRL1, GAP43, NTSR1 | L3MBTL1 269/4885EPHX1 1742/4885HTR6 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.