Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 7/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287861 | 0.77 | — | — | |
| SCHEMBL16521392 | 0.75 | ANPEP (0.42) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL1726025 | 0.74 | ANPEP (0.46) | AKR1B1TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL8522636 | 0.71 | ANPEP (0.39) | AKR1B1TSHRANPEPCES2CES1 | |
| SCHEMBL10584179 | 0.70 | — | — | |
| SCHEMBL9561943 | 0.70 | — | — | |
| SCHEMBL21154909 | 0.68 | ANPEP (0.40) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| Hexane SCHEMBL27816104 | 0.68 | AKR1B1 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexane SCHEMBL7024948 | 0.68 | AKR1B1 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexane SCHEMBL9670901 | 0.66 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111629746-B | Charge switchable polymer depot for glucose-triggered insulin delivery with ultra-fast response | 北卡罗来纳州立大学 | 2024-04-16 | — | — | CN | disclosed |
| US-11813352-B2 | Charge-switchable polymeric depot for glucose-triggered insulin delivery with ultrafast response | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-20200360269-A1 | CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE | NORTH CAROLINA STATE UNIVERSITY | 2020-11-19 | — | — | US | disclosed |
| EP-3713594-A1 | CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE | North Carolina State University (US) | 2020-09-30 | — | — | EP | disclosed |
| CN-111629746-A | Charge switchable polymer depot for glucose triggered insulin delivery with ultra-fast response | 北卡罗来纳州立大学 | 2020-09-04 | — | — | CN | disclosed |
| WO-2019104006-A1 | CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-05-31 | — | — | WO | disclosed |
| US-10180435-B2 | Method of surface modification by proteins for analyte preconcentration for desorption-ionization mass spectrometry techniques and for immunochemical assays | MIKROBIOLOGICKY USTAV AV CR, V.V.I. | 2019-01-15 | — | — | US | disclosed |
| EP-3194943-B1 | METHOD OF SURFACE MODIFICATION BY PROTEINS FOR ANALYTE PRECONCENTRATION FOR DESORPTION-IONIZATION MASS SPECTROMETRY TECHNIQUES AND FOR IMMUNOCHEMICAL ASSAYS | NOVAK PETR (CZ) | 2018-09-12 | — | — | EP | disclosed |
| US-20170242030-A1 | Method of Surface Modification by Proteins for Analyte Preconcentration for Desorption-Ionization Mass Spectrometry Techniques and for Immunochemical Assays | MIKROBIOLOGICKY USTAV AV CR, V.V.I. | 2017-08-24 | — | — | US | disclosed |
| EP-3194943-A1 | METHOD OF SURFACE MODIFICATION BY PROTEINS FOR ANALYTE PRECONCENTRATION FOR DESORPTION-IONIZATION MASS SPECTROMETRY TECHNIQUES AND FOR IMMUNOCHEMICAL ASSAYS | Novak, Petr (CZ) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016041531-A1 | METHOD OF SURFACE MODIFICATION BY PROTEINS FOR ANALYTE PRECONCENTRATION FOR DESORPTION-IONIZATION MASS SPECTROMETRY TECHNIQUES AND FOR IMMUNOCHEMICAL ASSAYS | NOVAK PETR (CZ) | 2016-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11813352-B2 | Charge-switchable polymeric depot for glucose-triggered insulin delivery with ultrafast response | IAPP, GPR119, INSR | AKR1B1 4759/4885GPR84 2779/4885PPARG 801/4885 |
| US-20200360269-A1 | CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE | IAPP, GPR119, INSR | AKR1B1 4759/4885GPR84 2779/4885PPARG 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.