SCHEMBL17607352

SCHEMBL17607352

C=CC(C(=O)O)N(C=CCc1cccnc1)C(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.37
KDM4E B2RXH2 1/20 0.37
TBXAS1 P24557 5/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RIPK1 Q13546 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
SLC1A5 Q15758 1/20 0.35
LMNA P02545 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17607354 0.78 TBXAS1 (0.42) CYP3A4TBXAS1
SCHEMBL17607353 0.75 TBXAS1 (0.40) CYP3A4TBXAS1RIPK1NAPRTLMNA
SCHEMBL29715367 0.69 LMNA (0.44) CYP3A4KDM4ETBXAS1RIPK1NAPRT
SCHEMBL5205285 0.69 LMNA (0.44) CYP3A4KDM4ETBXAS1RIPK1NAPRT
SCHEMBL23092737 0.69 LMNA (0.44) CYP3A4KDM4ETBXAS1RIPK1NAPRT
SCHEMBL25178693 0.68 CYP3A4 (0.44) CYP3A4KDM4ETBXAS1RIPK1NAPRT
SCHEMBL5890773 0.68 RIPK1 (0.63) CYP3A4RIPK1NAPRTLMNARAB9A
SCHEMBL17607360 0.67 KDM4E (0.46) CYP3A4KDM4ETBXAS1NAPRTLMNA
SCHEMBL17607359 0.67 KDM4E (0.46) CYP3A4KDM4ETBXAS1NAPRTLMNA
SCHEMBL7332333 0.67 RIPK1 (0.51) CYP3A4RIPK1NAPRTLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016042280-A1 CONJUGATES OF AMINO ACID-PYRIDINE/PYRIDINIUM AND USES THEREOF AS BIOCIDAL AGENTS Université de Nice Sophia Antipolis (FR) 2016-03-24 WO disclosed