Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42303 | 0.90 | BCHE (0.65) | BCHERAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL22265220 | 0.85 | APP (0.60) | BCHENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11714868 | 0.85 | MEN1 (0.67) | BCHEARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6608023 | 0.81 | ALDH1A1 (0.56) | ARRAB9AHPGDMEN1KMT2A | |
| SCHEMBL19382100 | 0.81 | AR (0.59) | BCHEARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2113895 | 0.80 | CYP1A2 (0.57) | BCHEARNPC1RAB9ASMN1; SMN2 | |
| Sulfurous Acid SCHEMBL28555351 | 0.79 | LMNA (0.51) | BCHELTA4HCYP1A2CYP2C19 | |
| SCHEMBL17609128 | 0.79 | ALOX5 (0.54) | BCHEAR | |
| SCHEMBL1465278 | 0.79 | KMT2A (0.70) | BCHEARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL866939 | 0.79 | NPC1 (0.60) | BCHEARNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193601-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044429-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |