SCHEMBL1761096

SCHEMBL1761096

C=CC(=O)NC(O)OCC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
ACACB O00763 2/20 0.39
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
CYP2C19 P33261 1/20 0.33
HPGD P15428 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3836751 0.82 TSHR (0.46) TSHRACACBALDH1A1MAPK1ZDHHC20
SCHEMBL9485030 0.82 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL7698482 0.82 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL368428 0.82 TSHR (0.56) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL1070152 0.81 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL10340177 0.81 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL6580192 0.78 TSHR (0.47) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL660975 0.77 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL3394077 0.77 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL10340176 0.77 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2217827-B1 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORP (US) 2020-06-03 EP disclosed
US-8490916-B2 Suspension system for aircraft auxiliary power unit with elastomeric member LORD CORPORATION (US) 2013-07-23 US disclosed
US-20130092788-A1 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORPORATION 2013-04-18 US disclosed
US-7947751-B2 Expandable resins NOVA CHEMICALS INC. (US) 2011-05-24 US disclosed
EP-2217827-A2 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER Lord Corporation (US) 2010-08-18 EP disclosed
EP-2178961-A1 PROCESS FOR MAKING POLYOLEFIN CLAY NANOCOMPOSITES Nova Chemicals Inc. (US) 2010-04-28 EP disclosed
US-20100056653-A1 EXPANDABLE RESINS NOVA CHEMICALS INC. (US) 2010-03-04 US disclosed
US-20100038471-A1 Suspension system for aircraft auxiliary power unit with elastomeric member LORD CORPORATION (US) 2010-02-18 US disclosed
US-7638559-B2 Unexpanded resin bead of particle size 0.001-10 mm and containing continuous phase and particulate dispersed phase; continuous phase includes one or more elastomeric polymers; dispersed phase includes one or more homo- and/or copolymers containing repeat units from aryl polymerizable monomers; toughness NOVA CHEMICALS INC. (US) 2009-12-29 US disclosed
WO-2009054926-A2 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORPORATION (US) 2009-04-30 WO disclosed
EP-1483348-A1 FLEXIBLE COATINGS FOR ELASTOMER SUBSTRATES Lord Corporation (US) 2004-12-08 EP disclosed
US-6777026-B2 FILM FORMING ELASTOMER, A ROOM TEMPERATURE CURING AGENT, AND THERMALLY CONDUCTIVE METAL PARTICLES; PROTECTIVE LORD CORPORATION 2004-08-17 US disclosed
WO-2004033573-A1 FLEXIBLE EMISSIVE COATINGS FOR ELASTOMER SUBSTRATES LORD CORPORATION (US) 2004-04-22 WO disclosed
US-20040068036-A1 Flexible emissive coatings for elastomer substrates LORD CORPORATION 2004-04-08 US disclosed
WO-2004011536-A1 AMBIENT CURED COATINGS AND COATED RUBBER PRODUCTS THEREFROM LORD CORPORATION (US) 2004-02-05 WO disclosed
US-20040018312-A1 Ambient cured coatings and coated rubber products therefrom LORD CORPORATION 2004-01-29 US disclosed
WO-2003076537-A1 FLEXIBLE COATINGS FOR ELASTOMER SUBSTRATES LORD CORPORATION (US) 2003-09-18 WO disclosed
US-20030152790-A1 Room temperature curable functionalized HNBR coating LORD CORPORATION 2003-08-14 US disclosed
US-6187867-B1 CURABLE; CONTROLLING RATIOS ZEON CHEMICALS L.P. 2001-02-13 US disclosed
EP-1038917-A1 Hydrogenated nitrile rubber compositions containing thermoplastic polyolefins Zeon Chemicals, L.P. (US) 2000-09-27 EP disclosed