SCHEMBL3394077

SCHEMBL3394077

C=CC(=O)NC(OC)OCC

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ACACB O00763 2/20 0.38
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
TGM2 P21980 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7698482 0.90 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL7693766 0.84 TSHR (0.56) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9485030 0.79 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL368428 0.79 TSHR (0.56) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9262683 0.78 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL1761096 0.77 TSHR (0.48) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL29236235 0.76 TSHR (0.47) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL6580192 0.76 TSHR (0.47) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL15134979 0.74 TGFBR1 (0.42) ALDH1A1
SCHEMBL10340176 0.74 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3114164-B1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES INC (US) 2025-07-02 EP disclosed
US-9976055-B2 Lower temperature cure coating compositions KING INDUSTRIES (US) 2018-05-22 US disclosed
US-20150197665-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 US disclosed
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 US disclosed
US-8431730-B2 Sulfonate esters as latent acid catalysts KING INDUSTRIES (US) 2013-04-30 US disclosed
EP-2203519-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS King Industries (US) 2010-07-07 EP disclosed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 US disclosed
WO-2009045466-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2009-04-09 WO disclosed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4469832-A SPRAYABLE COATINGS PPG INDUSTRIES, INC. (US) 1984-09-04 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
US-4417022-A SOLVENT-FREE PPG INDUSTRIES, INC. (US) 1983-11-22 US disclosed
US-4343925-A POLYESTERS PPG INDUSTRIES, INC. (US) 1982-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA TSHR 4219/4885ACACB 3391/4885ALDH1A1 3647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.