SCHEMBL368428

SCHEMBL368428

C=CC(=O)NC(C)OCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
ACACB O00763 2/20 0.43
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
CYP2C19 P33261 1/20 0.34
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.31
TGM2 P21980 1/20 0.31
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
KMT2A Q03164 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11159463 0.84 TSHR (0.52) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9485030 0.83 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL7698482 0.83 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9293036 0.82 TSHR (0.54) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL1761096 0.82 TSHR (0.48) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL5685783 0.81 TSHR (0.48) TSHRACACBALDH1A1MAPK1ZDHHC20
SCHEMBL476498 0.80 TSHR (0.52) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL6580192 0.80 TSHR (0.47) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL11230118 0.80 ALDH1A1 (0.42) TSHRALDH1A1LMNAMEN1KMT2A
SCHEMBL2875341 0.79 TSHR (0.43) TSHRACACBZDHHC20ZDHHC2TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264622-A1 MULTI-COMPONENT RESPONSIVE COPOLYMERS AND APPLICATIONS THEREOF AESCULA TECH, INC. (US) 2025-12-26 WO claimed
US-20250382404-A1 MULTI-COMPONENT RESPONSIVE COPOLYMERS AND APPLICATIONS THEREOF AESCULATECH INC (US) 2025-12-18 US claimed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN claimed
US-20220119569-A1 Curable and Solvent Soluble Formulations and Methods of Making and Using Therof POLY6 TECHNOLOGIES, INC. 2022-04-21 US claimed
US-20200062877-A1 Curable and Solvent Soluble Formulations and Methods of Making and Using Therof POLY6 TECHNOLOGIES, INC. 2020-02-27 US claimed
WO-2018156766-A2 CURABLE AND SOLVENT SOLUBLE FORMULATIONS AND METHODS OF MAKING AND USING THEREOF POLY6 TECHNOLOGIES, INC. (US) 2018-08-30 WO claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
EP-2267048-B1 FLUOROPOLYMER AND WATER-REPELLENT AND OIL-REPELLENT AGENT DAIKIN IND LTD (JP) 2016-10-12 EP claimed
US-20140335610-A1 CELL CULTURE SUBSTRATE, AND METHOD FOR MANUFACTURING SAME TOKYO WOMEN'S MEDICAL UNIVERSITY (JP) 2014-11-13 US claimed
CN-103403117-A Optical film having adhesive agent, and optical laminated body in which same is used SUMITOMO CHEMICAL CO 2013-11-20 CN claimed
US-8211991-B1 Thermo-gelling matrices and related methods for microchannel DNA sequencing NORTHWESTERN UNIVERSITY (US) 2012-07-03 US claimed
EP-1829896-B1 PROCESS FOR PRODUCTION OF ORGANIC-INORGANIC HYBRID HYDROGEL, CELL CULTURE SUBSTRATE COMPRISING THE SAME, AND ANTIFOGGING MATERIAL COMPRISING DRIED PRODUCT THEREOF KAWAMURA INST CHEM RES (JP) 2010-06-16 EP claimed
US-7682497-B1 Thermo-gelling matrices for microchannel DNA sequencing NORTHWESTERN UNIVERSITY (US) 2010-03-23 US claimed
JP-62089647-A None JP disclosed
EP-4745227-A1 GRAFT METHOD, CULTURE CARRIER SUBSTRATE, PACKAGE, CULTURE CARRIER SUBSTRATE EQUIPPED WITH CELL SHEET, METHOD FOR PRODUCING CULTURE CARRIER SUBSTRATE EQUIPPED WITH CELL SHEET, CRYOPRESERVATION METHOD, AND FROZEN PRODUCT OF CULTURE CARRIER SUBSTRATE EQUIPPED WITH CELL SHEET Central Glass Company, Limited (JP) 2026-05-20 EP disclosed
US-12630795-B2 Cell culture substrate, method for producing cell culture substrate, and method for producing spheroids TOSOH CORPORATION (JP) 2026-05-19 US disclosed
EP-1806152-A1 DRUG FOR EXTERNAL USE AND ADHESIVE PATCH HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2007-07-11 EP disclosed
EP-1788073-A1 POROUS SHEET MEMBER FOR CELL CULTURE AND, UTILIZING THE SAME, BIOREACTOR AND CULTURING METHOD Kyushu Institute of Technology (JP) 2007-05-23 EP disclosed
JP-S6289647-A NOVEL VINYL COMPOUND AGENCY OF IND SCIENCE & TECHNOL 1987-04-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630795-B2 Cell culture substrate, method for producing cell culture substrate, and method for producing spheroids MKI67, CCNB1, CD44 TSHR 1378/4885ACACB 523/4885ALDH1A1 1760/4885
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 TSHR 4448/4885ACACB 496/4885ALDH1A1 2228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.