SCHEMBL6580192

SCHEMBL6580192

C=CC(=O)NC(CC)OCC

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
ACACB O00763 2/20 0.38
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL660975 0.87 TSHR (0.45) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL8526201 0.85 TSHR (0.44) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL5207256 0.82 TSHR (0.48) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL368428 0.80 TSHR (0.56) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9485030 0.80 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL7698482 0.80 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL5824315 0.80 TSHR (0.39) TSHRACACBZDHHC20ZDHHC2CYP2C19
SCHEMBL18124154 0.79 TSHR (0.50) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL1761096 0.78 TSHR (0.48) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL10487230 0.78 TSHR (0.48) TSHRACACBALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267048-B1 FLUOROPOLYMER AND WATER-REPELLENT AND OIL-REPELLENT AGENT DAIKIN IND LTD (JP) 2016-10-12 EP claimed
US-20030220459-A1 Heat-sensitive water soluble copolymers based on(poly)ethoxylated(meth) acrylate, method for making same and use for preparing adhesive films and binders for textiles webs ATOFINA (FR) 2003-11-27 US claimed
EP-1297034-A2 HEAT-SENSITIVE WATER SOLUBLE COPOLYMERS BASED ON (POLY)ETHOXYLATED (METH)ACRYLATE, METHOD FOR MAKING SAME AND USE FOR PREPARING ADHESIVE FILMS AND BINDERS FOR TEXTILE WEBS Atofina (FR) 2003-04-02 EP claimed
US-20020035198-A1 Novel water-soluble (co) polymers containing quaternary amino groups, their manufacture and their use ATOFINA (FR) 2002-03-21 US claimed
WO-2002000743-A2 HEAT-SENSITIVE WATER SOLUBLE COPOLYMERS BASED ON (POLY)ETHOXYLATED (METH)ACRYLATE, METHOD FOR MAKING SAME AND USE FOR PREPARING ADHESIVE FILMS AND BINDERS FOR TEXTILE WEBS ATOFINA (FR) 2002-01-03 WO claimed
CN-100415812-C Photo-cured and stabilized coatings CIBA SC HOLDING AG (CH) 2008-09-03 CN disclosed
CN-1788045-A Photo-cured and stabilized coatings CIBA SC HOLDING AG (CH) 2006-06-14 CN disclosed
EP-1412097-A1 METHOD FOR HYDROPHILIC MODIFICATION OF A SUBSTRATE USING A TREATMENT IN AN AQUEOUS MEDIUM WITH A WATER SOLUBLE AND HEAT-SENSITIVE POLYMER Atofina (FR) 2004-04-28 EP disclosed
US-20030220459-A1 Heat-sensitive water soluble copolymers based on(poly)ethoxylated(meth) acrylate, method for making same and use for preparing adhesive films and binders for textiles webs ATOFINA (FR) 2003-11-27 US disclosed
EP-1297034-A2 HEAT-SENSITIVE WATER SOLUBLE COPOLYMERS BASED ON (POLY)ETHOXYLATED (METH)ACRYLATE, METHOD FOR MAKING SAME AND USE FOR PREPARING ADHESIVE FILMS AND BINDERS FOR TEXTILE WEBS Atofina (FR) 2003-04-02 EP disclosed
US-20020035198-A1 Novel water-soluble (co) polymers containing quaternary amino groups, their manufacture and their use ATOFINA (FR) 2002-03-21 US disclosed
EP-1179552-A1 New water soluble (co)polymers with quaternary amino groups, their preparation and their use Atofina (FR) 2002-02-13 EP disclosed
WO-2002000743-A2 HEAT-SENSITIVE WATER SOLUBLE COPOLYMERS BASED ON (POLY)ETHOXYLATED (METH)ACRYLATE, METHOD FOR MAKING SAME AND USE FOR PREPARING ADHESIVE FILMS AND BINDERS FOR TEXTILE WEBS ATOFINA (FR) 2002-01-03 WO disclosed
WO-2001078907-A1 METHOD FOR HYDROPHILIC MODIFICATION OF A SUBSTRATE USING A TREATMENT IN AN AQUEOUS MEDIUM WITH A WATER SOLUBLE AND HEAT-SENSITIVE POLYMER ATOFINA (FR) 2001-10-25 WO disclosed