Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 8/20 | 0.39 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PCNA | P12004 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584374 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BACEPTPN1THRB | |
| SCHEMBL6845190 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BACEPTPN1THRB | |
| SCHEMBL12584373 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BACEPTPN1THRB | |
| SCHEMBL5177146 | 0.81 | THRB (0.60) | ITGB3ITGA2BACETHRBTHRA | |
| SCHEMBL5177770 | 0.81 | THRB (0.60) | ITGB3ITGA2BACETHRBTHRA | |
| SCHEMBL8205060 | 0.81 | THRB (0.60) | ITGB3ITGA2BACETHRBTHRA | |
| SCHEMBL13952220 | 0.80 | THRB (0.47) | ITGB3ITGA2BACEPTPN1THRB | |
| SCHEMBL12642759 | 0.79 | THRB (0.44) | ITGB3ITGA2BACEPTPN1THRB | |
| SCHEMBL16124513 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BACEPTPN1THRB | |
| SCHEMBL14484751 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BACEPTPN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289395-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof | NANOPHARMACEUTICALS LLC (US) | 2016-03-22 | — | — | US | disclosed |