Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240983 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTTDP1LMNAKDM4E | |
| SCHEMBL29674811 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTTDP1LMNAKDM4E | |
| SCHEMBL12755077 | 0.96 | HTT (0.50) | ALDH1A1HTTTDP1LMNAKDM4E | |
| SCHEMBL20943656 | 0.84 | TDP1 (0.40) | TDP1LMNAKDM4EMEN1THRB | |
| SCHEMBL10372242 | 0.79 | MMP2 (0.45) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL12727918 | 0.78 | USP7 (0.44) | MAPTMEN1BLMKMT2A | |
| SCHEMBL14552147 | 0.78 | CRHR1 (0.47) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| Bathocuproine SCHEMBL4393344 | 0.78 | CRHR1 (0.39) | ALDH1A1TDP1LMNAKDM4EMAPT | |
| SCHEMBL10334284 | 0.78 | MMP2 (0.44) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| Bathocuproine SCHEMBL38659029 | 0.76 | CRHR1 (0.47) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106706578-A | Fluorescence detection method for hydrolase activity | 南京理工大学 | 2017-05-24 | — | — | CN | claimed |
| US-20200232993-A1 | METHODS AND COMPOSITIONS FOR FLUORESCENT AND COLORIMETRIC PROTEIN QUANTITATION | PIERCE BIOTECHNOLOGY, INC. | 2020-07-23 | — | — | US | disclosed |
| WO-2019014674-A1 | METHODS AND COMPOSITIONS FOR FLUORESCENT AND COLORIMETRIC PROTEIN QUANTITATION | PIERCE BIOTECHNOLOGY, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| CN-106706578-A | Fluorescence detection method for hydrolase activity | 南京理工大学 | 2017-05-24 | — | — | CN | disclosed |
| US-9290528-B1 | Light-activated compounds | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2016-03-22 | — | — | US | disclosed |