Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612981 | 0.91 | BRAF (0.39) | BRAF | |
| SCHEMBL12398177 | 0.86 | ABL1 (0.49) | BRAF | |
| SCHEMBL17612934 | 0.82 | MCHR1 (0.43) | BRAF | |
| SCHEMBL17612985 | 0.82 | BRAF (0.38) | BRAF | |
| SCHEMBL17612996 | 0.81 | BRAF (0.40) | BRAF | |
| SCHEMBL13960481 | 0.79 | BRAF (0.40) | BRAF | |
| SCHEMBL12398414 | 0.79 | ABL1 (0.50) | BRAF | |
| SCHEMBL13959986 | 0.79 | ABL1 (0.34) | BRAF | |
| SCHEMBL12465106 | 0.79 | ABL1 (0.48) | BRAF | |
| SCHEMBL12398140 | 0.79 | ABL1 (0.51) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |