Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 6/20 | 0.42 |
| ▸ | BRAF | P15056 | 12/20 | 0.41 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612980 | 0.91 | BRAF (0.42) | MCHR1ABL1BRAFGPR142 | |
| SCHEMBL12398219 | 0.86 | GPR142 (0.54) | MCHR1ABL1BRAFGPR142 | |
| SCHEMBL17612910 | 0.82 | BRAF (0.40) | BRAF | |
| SCHEMBL12398225 | 0.78 | BRAF (0.54) | ABL1BRAFGPR142 | |
| SCHEMBL17612983 | 0.77 | TEK (0.43) | BRAF | |
| SCHEMBL17612981 | 0.77 | BRAF (0.39) | MCHR1BRAF | |
| SCHEMBL12398231 | 0.76 | GPR142 (0.55) | ABL1BRAFGPR142 | |
| SCHEMBL17612985 | 0.76 | BRAF (0.38) | ABL1BRAF | |
| SCHEMBL12398015 | 0.75 | BRAF (0.57) | ABL1BRAFGPR142 | |
| SCHEMBL17612946 | 0.75 | ABL1 (0.45) | ABL1GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |