Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.51 |
| ▸ | BCR | P11274 | 11/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 6/20 | 0.48 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612913 | 0.88 | ABL1 (0.48) | ABL1BCRKITBRAFEGFR | |
| SCHEMBL12397882 | 0.86 | ABL1 (0.64) | ABL1BCR | |
| SCHEMBL17612997 | 0.79 | DDR2 (0.50) | ABL1BCRKITBRAF | |
| SCHEMBL17612975 | 0.79 | DDR2 (0.45) | ABL1BCRKIT | |
| SCHEMBL12396884 | 0.78 | ABL1 (0.55) | ABL1BCR | |
| SCHEMBL12397884 | 0.77 | ABL1 (0.69) | ABL1BCR | |
| SCHEMBL12397827 | 0.77 | ABL1 (0.69) | ABL1BCR | |
| SCHEMBL17612957 | 0.77 | ABL1 (0.38) | ABL1BCRBRAFEGFR | |
| SCHEMBL12397845 | 0.77 | ABL1 (0.77) | ABL1BCR | |
| SCHEMBL12397854 | 0.77 | ABL1 (0.70) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |