Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.48 |
| ▸ | BCR | P11274 | 13/20 | 0.48 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | BRAF | P15056 | 5/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612912 | 0.88 | ABL1 (0.51) | ABL1BCREGFRBRAFKIT | |
| SCHEMBL12397887 | 0.85 | ABL1 (0.62) | ABL1BCR | |
| SCHEMBL17612957 | 0.80 | ABL1 (0.38) | ABL1BCREGFRBRAF | |
| SCHEMBL17612946 | 0.78 | ABL1 (0.45) | ABL1BCRKIT | |
| SCHEMBL12465323 | 0.78 | ABL1 (0.54) | ABL1BCR | |
| SCHEMBL13960494 | 0.78 | ABL1 (0.39) | ABL1BCREGFRBRAFKIT | |
| SCHEMBL17612985 | 0.78 | BRAF (0.38) | ABL1BCREGFRBRAF | |
| SCHEMBL17612910 | 0.77 | BRAF (0.40) | BRAF | |
| SCHEMBL17612997 | 0.76 | DDR2 (0.50) | ABL1BCRBRAFKIT | |
| SCHEMBL12397799 | 0.75 | ABL1 (0.61) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |