Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 17/20 | 0.50 |
| ▸ | DDR1 | Q08345 | 13/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 6/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 3/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397448 | 0.86 | ABL1 (0.50) | DDR2ABL1BCR | |
| SCHEMBL17612975 | 0.86 | DDR2 (0.45) | DDR2DDR1KITABL1BCR | |
| SCHEMBL17612977 | 0.85 | BRAF (0.46) | DDR1KITABL1BRAF | |
| SCHEMBL17612946 | 0.84 | ABL1 (0.45) | DDR2KITABL1NTRK3BCR | |
| SCHEMBL17612960 | 0.82 | DDR2 (0.49) | DDR2DDR1KITABL1BRAF | |
| SCHEMBL12397101 | 0.82 | GPR142 (0.48) | DDR2ABL1BRAFBCR | |
| SCHEMBL12397002 | 0.81 | ABL1 (0.51) | DDR2DDR1ABL1BRAFBCR | |
| SCHEMBL12397318 | 0.81 | ABL1 (0.46) | DDR2DDR1KITABL1BCR | |
| SCHEMBL12397444 | 0.79 | GPR142 (0.50) | DDR2ABL1BRAFBCR | |
| SCHEMBL13960449 | 0.79 | DDR2 (0.47) | DDR2DDR1KITABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |