Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 8/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 4/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460078 | 0.85 | JAK2 (0.43) | JAK2CDK5CDK5R1JAK3TERT | |
| SCHEMBL3460724 | 0.78 | JAK2 (0.46) | JAK2CDK5CDK5R1JAK3TERT | |
| SCHEMBL12968601 | 0.77 | CDK5 (0.50) | JAK2CDK5CDK5R1JAK3KMT2A | |
| SCHEMBL17613784 | 0.74 | CDK5 (0.47) | JAK2CDK5CDK5R1JAK3KMT2A | |
| SCHEMBL18689025 | 0.72 | TERT (0.52) | JAK2TERTMPO | |
| SCHEMBL3461880 | 0.72 | JAK2 (0.53) | JAK2JAK3TERTMPOKMT2A | |
| SCHEMBL3460014 | 0.70 | TERT (0.48) | JAK2JAK3TERTMPOKMT2A | |
| SCHEMBL17613793 | 0.70 | ACHE (0.47) | CDK5CDK5R1KMT2AMEN1GAA | |
| SCHEMBL3461165 | 0.69 | TERT (0.57) | JAK2TERTMPO | |
| SCHEMBL1035716 | 0.67 | CDK5 (0.49) | JAK2CDK5CDK5R1JAK3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326327-B1 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | STANFORD RES INST INT (US) | 2016-03-23 | — | — | EP | disclosed |