Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 5/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968601 | 0.83 | CDK5 (0.50) | CDK5CDK5R1MAPTALDH1A1NPC1 | |
| SCHEMBL3460583 | 0.81 | KIF11 (0.44) | CDK5CDK5R1MAPTALDH1A1RAB9A | |
| SCHEMBL17613793 | 0.79 | ACHE (0.47) | CDK5CDK5R1MAPTALDH1A1NPC1 | |
| SCHEMBL23223694 | 0.76 | JAK2 (0.43) | CDK5CDK5R1MAPTALDH1A1KMT2A | |
| SCHEMBL15201968 | 0.76 | MAPT (0.58) | CDK5CDK5R1MAPTALDH1A1KMT2A | |
| SCHEMBL1920809 | 0.75 | KIF11 (0.56) | CDK5CDK5R1MAPTALDH1A1NPC1 | |
| SCHEMBL14255879 | 0.75 | KMT2A (0.55) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL17613802 | 0.74 | JAK2 (0.44) | CDK5CDK5R1KMT2AJAK2MEN1 | |
| SCHEMBL7123791 | 0.73 | KEAP1 (0.54) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL20865127 | 0.73 | KIF11 (0.47) | CDK5CDK5R1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326327-B1 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | STANFORD RES INST INT (US) | 2016-03-23 | — | — | EP | disclosed |