Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117399 | 0.75 | MAPK1 (0.34) | MMP2MMP9 | |
| SCHEMBL27848662 | 0.71 | P2RX7 (0.37) | L3MBTL1P2RX7 | |
| SCHEMBL17946424 | 0.68 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL13185695 | 0.65 | ACE (0.36) | — | |
| SCHEMBL21424968 | 0.59 | ITGB1 (0.39) | L3MBTL1P2RX7 | |
| SCHEMBL24464081 | 0.58 | — | — | |
| SCHEMBL17034428 | 0.57 | ACE (0.37) | — | |
| SCHEMBL1587390 | 0.57 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL10073516 | 0.57 | — | — | |
| SCHEMBL14827922 | 0.57 | P2RX7 (0.43) | L3MBTL1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160287563-A1 | Cysteine Prodrugs | PROMENTIS PHARMACEUTICALS, INC. (US) | 2016-10-06 | — | — | US | disclosed |
| US-9457014-B2 | Cysteine prodrugs | PROMENTIS PHARMACEUTICALS, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160081987-A1 | Cysteine Prodrugs | PROMENTIS PHARMACEUTICALS, INC. (US) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287563-A1 | Cysteine Prodrugs | SLC7A11, GCLC, CTH | MMP2 2984/4885MMP9 3226/4885TDP1 1007/4885 |
| US-20160081987-A1 | Cysteine Prodrugs | SLC7A11, GCLC, CTH | MMP2 2984/4885MMP9 3226/4885TDP1 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.