Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 18/20 | 0.58 |
| ▸ | PARG | Q86W56 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17619869 | 0.85 | TRPA1 (0.57) | TRPA1 | |
| SCHEMBL17619778 | 0.83 | TRPA1 (0.56) | TRPA1PARGGRIN1GRIN2B | |
| SCHEMBL17619749 | 0.82 | TRPA1 (0.57) | TRPA1PARGGRIN1GRIN2B | |
| SCHEMBL17619988 | 0.76 | TRPA1 (0.52) | TRPA1 | |
| SCHEMBL21861722 | 0.74 | TRPA1 (0.51) | TRPA1 | |
| SCHEMBL19396062 | 0.74 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL17619775 | 0.71 | TRPA1 (0.56) | TRPA1PARGGRIN1GRIN2B | |
| SCHEMBL20011251 | 0.70 | TRPA1 (0.36) | TRPA1PARGGRIN1GRIN2B | |
| SCHEMBL17619616 | 0.69 | TRPA1 (0.53) | TRPA1PARGGRIN1GRIN2B | |
| SCHEMBL17620157 | 0.68 | TRPA1 (0.54) | TRPA1PARGGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044792-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2016-03-24 | — | — | WO | disclosed |