Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.49 |
| ▸ | PARG | Q86W56 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620010 | 0.79 | TRPA1 (0.57) | TRPA1GRIN1GRIN2BPARGGABRA5 | |
| SCHEMBL17619775 | 0.78 | TRPA1 (0.56) | TRPA1GRIN1GRIN2BPARGGABRA5 | |
| SCHEMBL17619754 | 0.77 | TRPA1 (0.51) | TRPA1GRIN1GRIN2B | |
| SCHEMBL17609714 | 0.76 | ADORA2B (0.59) | TRPA1GRIN1GRIN2BMAPT | |
| SCHEMBL17619608 | 0.74 | TRPA1 (0.52) | TRPA1GRIN1GRIN2BPARGMAPT | |
| SCHEMBL14969156 | 0.71 | TRPA1 (0.49) | TRPA1GRIN1GRIN2BPARGMAPT | |
| SCHEMBL17619605 | 0.70 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL17619749 | 0.70 | TRPA1 (0.57) | TRPA1GRIN1GRIN2BPARGGABRA5 | |
| SCHEMBL20129922 | 0.69 | GRIN1 (0.65) | TRPA1GRIN1GRIN2BPARGGABRA5 | |
| SCHEMBL29636008 | 0.69 | GRIN1 (0.65) | TRPA1GRIN1GRIN2BPARGGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044792-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2016-03-24 | — | — | WO | disclosed |