SCHEMBL644546

SCHEMBL644546

C=C(C)C(=O)OC.C=C(CC)C(=O)OCCCCCC.C=CC(=O)OC1CC2CCC1(C)C2(C)C

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
HTT P42858 3/20 0.47
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 3/20 0.47
KDM4E B2RXH2 3/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
PLA2G1B P04054 1/20 0.45
MAPK1 P28482 1/20 0.45
RAD52 P43351 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45
TSHR P16473 2/20 0.39
CYP2C19 P33261 1/20 0.38
EPHX2 P34913 1/20 0.37
ELANE P08246 2/20 0.36
GAA P10253 1/20 0.36
XBP1 P17861 1/20 0.36
CYP19A1 P11511 2/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645678 0.95 LMNA (0.48) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL5420419 0.94 HTT (0.42) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL644917 0.92 HTT (0.44) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL23855038 0.91 LMNA (0.52) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL8777327 0.91 LMNA (0.52) LMNAHTTMAPTNPSR1KDM4E
Acrylic Acid SCHEMBL3095853 0.89 LMNA (0.49) LMNAHTTMAPTNPSR1KDM4E
Methacrylic Acid SCHEMBL8777382 0.88 LMNA (0.50) LMNAHTTMAPTNPSR1KDM4E
Styrene SCHEMBL1762174 0.87 CYP2C19 (0.42) LMNAHTTMAPTNPSR1KDM4E
Methacrylic Acid SCHEMBL7080056 0.87 LMNA (0.49) LMNAHTTMAPTNPSR1KDM4E
SCHEMBL28319877 0.85 LMNA (0.50) LMNAHTTMAPTNPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070166259-A1 Cosmetic composition comprising a tensioning agent and a particular block ethylenic polymer L'OREAL (FR) 2007-07-19 US claimed
EP-1675558-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2006-07-05 EP claimed
WO-2005030155-A1 CONTINUOUS AQUEOUS PHASE-BASED PHOTOPROTECTIVE COMPOSITION CONTAINING A POLYMER COMPRISING AT LEAST TWO BLOCKS INCOMPATIBLE WITH EACH OTHER AND HAVING DIFFERENT GLASS TRANSITION TEMPERATURES L'ORÉAL (FR) 2005-04-07 WO claimed
WO-2005030158-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2005-04-07 WO claimed
WO-2023118526-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A (UN)SATURATED HYDROCARBON-BASED CHAIN AND A HYDROCARBON-BASED POLYMER L'OREAL (FR) 2023-06-29 WO disclosed
CN-107743392-B Oil-in-water emulsion composition 莱雅公司 2021-05-07 CN disclosed
EP-3341083-B1 OIL-IN-WATER EMULSION COMPOSITION OREAL (FR) 2021-03-24 EP disclosed
EP-1579845-B1 Cosmetic composition comprising a polyglycerolated silicone elastomer L'ORÉAL (FR) 2017-04-19 EP disclosed
US-9017704-B2 Composition comprising a block polymer and a film-forming agent L'OREAL (FR) 2015-04-28 US disclosed
US-8992903-B2 Composition comprising at least one block polymer and at least one gelling agent L'OREAL (FR) 2015-03-31 US disclosed
US-8728451-B2 Styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer, processes employing same and uses thereof L'OREAL (FR) 2014-05-20 US disclosed
US-8119110-B2 Film forming ethylene oxide-propylene oxide block polymer L'OREAL S.A. (FR) 2012-02-21 US disclosed
EP-1579845-A2 Cosmetic composition comprising a polyglycerolated silicone elastomer L'OREAL (FR) 2005-09-28 EP disclosed
US-20050106197-A1 Cosmetic composition comprising a block polymer and a non-volatile silicone oil L'OREAL S.A. (FR) 2005-05-19 US disclosed
CN-1615811-A Bilayered cosmetic product, uses thereof and kit-of-parts containing this product OREAL (FR) 2005-05-18 CN disclosed
US-20050095213-A1 Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product L'OREAL S.A. (FR) 2005-05-05 US disclosed
WO-2005030155-A1 CONTINUOUS AQUEOUS PHASE-BASED PHOTOPROTECTIVE COMPOSITION CONTAINING A POLYMER COMPRISING AT LEAST TWO BLOCKS INCOMPATIBLE WITH EACH OTHER AND HAVING DIFFERENT GLASS TRANSITION TEMPERATURES L'ORÉAL (FR) 2005-04-07 WO disclosed
WO-2005030158-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2005-04-07 WO disclosed
EP-1518534-A2 Bilayered cosmetic product, uses thereof and kit-of-parts containing this product. L'OREAL (FR) 2005-03-30 EP disclosed
US-20040120920-A1 Novel block polymers and cosmetic compositions and processes comprising them L'OREAL S.A. (FR) 2004-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050095213-A1 Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product CUTA, PRKACB, PRKDC LMNA 420/4885HTT 1602/4885MAPT 1381/4885
US-20040120920-A1 Novel block polymers and cosmetic compositions and processes comprising them FANCI, GDI2, TBCB LMNA 1755/4885HTT 607/4885MAPT 1240/4885
US-20070166259-A1 Cosmetic composition comprising a tensioning agent and a particular block ethylenic polymer CUTA, ERCC1, RAD23B LMNA 148/4885HTT 1918/4885MAPT 992/4885
US-20050106197-A1 Cosmetic composition comprising a block polymer and a non-volatile silicone oil KRT18, CUTA, DSG1 LMNA 799/4885HTT 3096/4885MAPT 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.