SCHEMBL17622233

SCHEMBL17622233

CC(C)(C)c1ccccc1N1C(=O)c2cccc(-n3c4ccccc4c4ccccc43)c2C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
LMNA P02545 2/20 0.39
NR1H2 P55055 2/20 0.36
NR1H3 Q13133 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
ALDH1A1 P00352 2/20 0.35
HSPA1A P0DMV8 1/20 0.35
PABPC1 P11940 1/20 0.35
TYMS P04818 1/20 0.34
DUSP3 P51452 1/20 0.34
RORC P51449 1/20 0.34
DPP4 P27487 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
TNNI3 P19429 1/20 0.33
HTT P42858 1/20 0.33
TNNT2 P45379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17622372 0.87 POLB (0.42) POLBLMNANR1H3ALDH1A1MAPT
SCHEMBL17622290 0.86 POLB (0.51) POLBLMNANR1H2NR1H3CA2
SCHEMBL19842564 0.85 NR1H2 (0.44) POLBLMNANR1H2KMT2AMEN1
SCHEMBL17622327 0.84 LMNA (0.46) POLBLMNANR1H2NR1H3KMT2A
SCHEMBL19421858 0.83 LMNA (0.56) POLBLMNANR1H2NR1H3KMT2A
SCHEMBL19842612 0.82 DPP4 (0.36) POLBLMNANR1H2KMT2AMEN1
SCHEMBL19842407 0.81 PDE6D (0.46) POLBLMNAKMT2AMEN1ALDH1A1
SCHEMBL17622328 0.81 HSPA1A (0.50) POLBLMNACA2CA9KMT2A
SCHEMBL19842477 0.80 NR1H2 (0.55) POLBLMNANR1H2CA2CA9
SCHEMBL17622234 0.80 HSPA1A (0.56) POLBLMNANR1H3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651394-B2 Organic molecules for use as emitters CYNORA GMBH (DE) 2020-05-12 US disclosed
EP-3246373-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2019-01-30 EP disclosed
EP-3137574-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2018-04-04 EP disclosed
EP-3246373-A1 ORGANIC MOLECULES FOR USE AS EMITTERS cynora GmbH (DE) 2017-11-22 EP disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
WO-2016042070-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2016-03-24 WO disclosed