Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17622233 | 0.87 | POLB (0.42) | POLBALDH1A1HTTMAPTGRM1 | |
| SCHEMBL17622290 | 0.86 | POLB (0.51) | POLBALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL19842380 | 0.85 | NR1H2 (0.44) | POLBALDH1A1L3MBTL1CASP1HTT | |
| SCHEMBL19848828 | 0.84 | HSPA1A (0.48) | POLBALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL19848838 | 0.83 | HSPA1A (0.44) | POLBALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL19842444 | 0.82 | NR1H2 (0.36) | POLBALDH1A1L3MBTL1HTTNR1H3 | |
| SCHEMBL17622327 | 0.82 | LMNA (0.46) | POLBNR1H3LMNA | |
| SCHEMBL19842428 | 0.81 | PDE6D (0.46) | POLBALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL17622328 | 0.81 | HSPA1A (0.50) | POLBALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL23515890 | 0.81 | NR1H2 (0.47) | POLBALDH1A1CASP1HTTGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10651394-B2 | Organic molecules for use as emitters | CYNORA GMBH (DE) | 2020-05-12 | — | — | US | disclosed |
| EP-3246373-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | cynora GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-20170288149-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2017-10-05 | — | — | US | disclosed |
| WO-2016042070-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |