SCHEMBL17622271

SCHEMBL17622271

Cc1cc(C)c(N2C(=O)c3cccc(N4c5ccccc5C(C)(C)c5ccccc54)c3C2=O)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.47
PGR P06401 7/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TYMS P04818 1/20 0.39
NR1H3 Q13133 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17622170 0.85 PGR (0.50) DPP4PGRMEN1KMT2ALMNA
SCHEMBL17643882 0.81 DPP4 (0.57) DPP4PGRMEN1KMT2ANR1H3
SCHEMBL17622268 0.80 PGR (0.49) PGRMEN1KMT2ATYMS
SCHEMBL14691582 0.79 NPSR1 (0.40) PGRMEN1KMT2ALMNAKDM4E
SCHEMBL24002953 0.78 DPP4 (0.47) DPP4MEN1KMT2ALMNASMN1; SMN2
SCHEMBL19421893 0.78 DPP4 (0.47) DPP4MEN1KMT2ALMNATYMS
SCHEMBL19838232 0.76 KMT2A (0.55) DPP4MEN1KMT2AKDM4EALDH1A1
SCHEMBL19834886 0.74 DPP4 (0.55) DPP4
SCHEMBL19365931 0.74 DPP4 (0.55) DPP4LMNASMN1; SMN2
SCHEMBL23892813 0.73 DPP4 (0.42) DPP4MEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651394-B2 Organic molecules for use as emitters CYNORA GMBH (DE) 2020-05-12 US disclosed
EP-3246373-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2019-01-30 EP disclosed
EP-3137574-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2018-04-04 EP disclosed
EP-3246373-A1 ORGANIC MOLECULES FOR USE AS EMITTERS cynora GmbH (DE) 2017-11-22 EP disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
WO-2016042070-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2016-03-24 WO disclosed