SCHEMBL17622170

SCHEMBL17622170

CC1(C)c2ccccc2N(c2cccc3c2C(=O)N(c2ccccc2N2C(=O)c4cccc(N5c6ccccc6C(C)(C)c6ccccc65)c4C2=O)C3=O)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGR P06401 10/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.41
DPP4 P27487 1/20 0.41
HSPA1A P0DMV8 1/20 0.40
PABPC1 P11940 1/20 0.40
TYMS P04818 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17622268 0.88 PGR (0.49) PGRMEN1KMT2AHSPA1APABPC1
SCHEMBL17622271 0.85 DPP4 (0.47) PGRMEN1KMT2ALMNADPP4
SCHEMBL17643882 0.84 DPP4 (0.57) PGRMEN1KMT2ADPP4
SCHEMBL17622174 0.80 DDB1 (0.42) PGRMEN1KMT2A
SCHEMBL13231539 0.78 KMT2A (0.47) PGRMEN1KMT2ALMNAPOLB
SCHEMBL19317084 0.76 PGR (0.59) PGRMEN1KMT2A
SCHEMBL19317087 0.76 PGR (0.55) PGRMEN1KMT2A
SCHEMBL20019729 0.76 RAB9A (0.39) PGRMEN1KMT2AHSPA1APABPC1
SCHEMBL19317120 0.75 PGR (0.50) PGRMEN1KMT2A
SCHEMBL17974877 0.75 PGR (0.36) PGRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651394-B2 Organic molecules for use as emitters CYNORA GMBH (DE) 2020-05-12 US disclosed
EP-3246373-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2019-01-30 EP disclosed
EP-3137574-B1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2018-04-04 EP disclosed
EP-3246373-A1 ORGANIC MOLECULES FOR USE AS EMITTERS cynora GmbH (DE) 2017-11-22 EP disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
US-20170288149-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2017-10-05 US disclosed
WO-2016042070-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2016-03-24 WO disclosed