Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31151022 | 0.84 | PDE4B (0.48) | HSD17B10ALDH1A1HPGDKDM4ETP53 | |
| SCHEMBL30666434 | 0.84 | CA12 (0.47) | GRM6HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL320812 | 0.84 | CA12 (0.47) | GRM6HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL8840548 | 0.84 | PDE4B (0.48) | HSD17B10ALDH1A1HPGDKDM4ETP53 | |
| SCHEMBL31468929 | 0.83 | TP53 (0.41) | GRM6HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL4231441 | 0.82 | ALDH1A1 (0.41) | HSD17B10ALDH1A1HPGDKDM4ETP53 | |
| SCHEMBL25303508 | 0.82 | DPP4 (0.43) | GRM6HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL843997 | 0.81 | ADORA3 (0.47) | GRM6HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL844466 | 0.81 | CA12 (0.45) | GRM6HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL23923034 | 0.81 | MAPT (0.47) | HSD17B10ALDH1A1HPGDKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727435-B1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | UNIV CARNEGIE MELLON (US) | 2026-02-18 | — | — | EP | disclosed |
| CN-111757935-B | Bivalent nucleic acid ligands and uses thereof | 卡耐基梅隆大学 | 2025-02-21 | — | — | CN | disclosed |
| EP-3727435-A1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-111757935-A | Bivalent nucleic acid ligand and use thereof | 卡耐基梅隆大学 | 2020-10-09 | — | — | CN | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-10370415-B2 | Divalent nucleobase compounds and uses therefor | CARNEGIE MELLON UNIVERSITY (US) | 2019-08-06 | — | — | US | disclosed |
| US-20160083434-A1 | DIVALENT NUCLEOBASE COMPOUNDS AND USES THEREFOR | CARNEGIE MELLON UNIVERSITY (US) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083434-A1 | DIVALENT NUCLEOBASE COMPOUNDS AND USES THEREFOR | DNTT, POLM, POLL | GRM6 3716/4885HSD17B10 4708/4885ALDH1A1 4313/4885 |
| US-10370415-B2 | Divalent nucleobase compounds and uses therefor | DNTT, POLM, POLL | GRM6 3716/4885HSD17B10 4708/4885ALDH1A1 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.