Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17622705 | 0.86 | KDM1A (0.44) | TP53HTR2CMEN1KMT2AKDM4E | |
| SCHEMBL17623034 | 0.82 | TP53 (0.38) | TP53MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL17622717 | 0.80 | MAPT (0.49) | MEN1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL17623049 | 0.76 | ACACB (0.36) | TP53MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16091163 | 0.74 | TP53 (0.45) | TP53MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16091174 | 0.71 | TP53 (0.43) | TP53MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16090980 | 0.70 | TP53 (0.42) | TP53MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16090970 | 0.70 | TP53 (0.42) | TP53MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9045898 | 0.69 | HTR2C (0.53) | HTR2CMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL30040822 | 0.69 | HTR2C (0.53) | HTR2CMEN1KMT2AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |