Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17622705 | 0.83 | KDM1A (0.44) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL17623034 | 0.81 | TP53 (0.38) | MAPK1ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL17623259 | 0.80 | TP53 (0.42) | TSHRALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL17622700 | 0.74 | MAPT (0.50) | MAPTSMN1; SMN2TSHRRXFP1POLB | |
| SCHEMBL17623049 | 0.73 | ACACB (0.36) | KDM4EKMT2AMEN1 | |
| SCHEMBL30297596 | 0.71 | MAPT (0.52) | MAPTSMN1; SMN2TSHRRXFP1POLB | |
| SCHEMBL16091163 | 0.69 | TP53 (0.45) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL11235006 | 0.69 | MAPT (0.69) | MAPTSMN1; SMN2TSHRRXFP1POLB | |
| SCHEMBL16091174 | 0.69 | TP53 (0.43) | SMN1; SMN2ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL2273815 | 0.68 | MAPT (0.61) | MAPTSMN1; SMN2TSHRRXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |