Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17622705 | 0.77 | KDM1A (0.44) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17623259 | 0.76 | TP53 (0.42) | TP53KDM4EMEN1NPC1RAB9A | |
| SCHEMBL17623034 | 0.75 | TP53 (0.38) | ACACBTP53AKT1KDM4EMEN1 | |
| SCHEMBL17622717 | 0.73 | MAPT (0.49) | KDM4EMEN1KMT2A | |
| SCHEMBL17623014 | 0.73 | JAK3 (0.44) | ACACB | |
| SCHEMBL16091163 | 0.68 | TP53 (0.45) | ACACBPDE2ATP53KDM4EMEN1 | |
| SCHEMBL17623352 | 0.65 | TP53 (0.41) | ACACBTP53KDM4EMEN1NPC1 | |
| SCHEMBL16091174 | 0.65 | TP53 (0.43) | ACACBTP53KDM4EMEN1NPC1 | |
| SCHEMBL16090980 | 0.64 | TP53 (0.42) | ACACBTP53KDM4EMEN1NPC1 | |
| SCHEMBL16090970 | 0.64 | TP53 (0.42) | ACACBTP53KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |