Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608449 | 0.83 | PTGER4 (0.51) | ELANEHDAC6PTGER4PTGDR2 | |
| SCHEMBL17624291 | 0.82 | ELANE (0.53) | ELANEPTGER4PTGDR2 | |
| SCHEMBL1214836 | 0.81 | ELANE (0.64) | ELANEPTGER4PTGDR2 | |
| SCHEMBL17608697 | 0.80 | AR (0.43) | ELANEACHEHDAC8PTGER4PTGDR2 | |
| SCHEMBL1216862 | 0.79 | CYP1A2 (0.51) | ELANEPTGER4PTGDR2 | |
| SCHEMBL17608381 | 0.77 | ELANE (0.46) | ELANEPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL17624290 | 0.77 | HRH1 (0.45) | POLBACHEPDE4APDE4BPDE4C | |
| SCHEMBL30602797 | 0.74 | CNR2 (0.53) | ELANEPOLBACHEBCHEPTGDR2 | |
| SCHEMBL17608644 | 0.74 | PTGER4 (0.51) | PTGER4 | |
| SCHEMBL13931862 | 0.73 | HDAC1 (0.50) | HDAC3HDAC1HDAC2HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |