SCHEMBL17624696

SCHEMBL17624696

Bc1ccccc1C(Br)Br

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655520 0.78 CYP1A2 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL13068682 0.74 GABRA1 (0.35) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL13760578 0.72 TRPA1 (0.30)
SCHEMBL5613958 0.72 GABRA1 (0.50) ALDH1A1CYP1A2CYP2C19
SCHEMBL5712842 0.71 MEN1 (0.40) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL29738572 0.71 MEN1 (0.40) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL13068680 0.69 IDO1 (0.36) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL14473089 0.69 IDO1 (0.36) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL305225 0.69 IDO1 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL4933638 0.69 CYP1A2 (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016044390-A1 BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS INTREXON CORPORATION (US) 2016-03-24 WO disclosed