Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634115 | 0.91 | FAAH (0.54) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL19687365 | 0.91 | CASP2 (0.62) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL17624918 | 0.89 | CASP2 (0.59) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL29078164 | 0.87 | CASP2 (0.66) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL29419660 | 0.87 | CASP2 (0.66) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL29379848 | 0.87 | CASP2 (0.66) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL25008201 | 0.86 | FAAH (0.62) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL14438830 | 0.84 | FAAH (0.61) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL15888712 | 0.84 | SMN1; SMN2 (0.60) | CASP2FAAHDNM1NAAAEPHX2 | |
| SCHEMBL17624903 | 0.84 | CASP2 (0.56) | CASP2FAAHDNM1NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |