Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909211 | 0.91 | GBA1 (0.42) | MAPK1GBA1 | |
| SCHEMBL2358722 | 0.85 | GBA1 (0.38) | GBA1 | |
| SCHEMBL18000449 | 0.84 | NOTUM (0.38) | GBA1 | |
| SCHEMBL18994622 | 0.84 | GBA1 (0.40) | MAPK1GBA1 | |
| SCHEMBL17625190 | 0.84 | GGPS1 (0.39) | MAPK1 | |
| SCHEMBL18994582 | 0.83 | GBA1 (0.55) | GBA1 | |
| SCHEMBL17601989 | 0.81 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL22856280 | 0.80 | GBA1 (0.43) | GBA1 | |
| SCHEMBL25884344 | 0.79 | NOTUM (0.49) | GBA1 | |
| SCHEMBL22788650 | 0.79 | MAOB (0.41) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | disclosed |
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CTNNB1, WNT3A, WNT1 | MAPK1 343/4885GBA1 2238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.