Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320678 | 0.90 | MAPK1 (0.41) | MAPK1KDM4ETP53MTNR1AMTNR1B | |
| SCHEMBL25606926 | 0.84 | TP53 (0.36) | TP53MTNR1AMTNR1BDPP4 | |
| SCHEMBL18000411 | 0.83 | NPSR1 (0.38) | MAPK1KDM4ETP53LTA4HDPP4 | |
| SCHEMBL17625567 | 0.81 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL22481985 | 0.78 | GLS (0.48) | — | |
| SCHEMBL24340637 | 0.77 | NR1H4 (0.39) | DPP4 | |
| SCHEMBL18994622 | 0.77 | GBA1 (0.40) | MAPK1MTNR1AMTNR1BLTA4H | |
| SCHEMBL17625190 | 0.77 | GGPS1 (0.39) | MAPK1 | |
| SCHEMBL18685242 | 0.77 | DPP4 (0.40) | DPP4 | |
| SCHEMBL22788650 | 0.76 | MAOB (0.41) | MAPK1MTNR1AMTNR1BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | claimed |
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-24 | — | — | US | claimed |
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CTNNB1, WNT3A, WNT1 | MAPK1 343/4885KDM4E 3792/4885TP53 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.